Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion

Insulin-secreting beta cells play an essential role in maintaining physiological blood glucose levels, and their dysfunction leads to the development of diabetes. To elucidate the signalling events regulating insulin secretion, we applied a recently developed phosphoproteomics workflow. We quantifie...

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Detalles Bibliográficos
Autores principales: Sacco, Francesca, Humphrey, Sean J., Cox, Jürgen, Mischnik, Marcel, Schulte, Anke, Klabunde, Thomas, Schäfer, Matthias, Mann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114537/
https://www.ncbi.nlm.nih.gov/pubmed/27841257
http://dx.doi.org/10.1038/ncomms13250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114537/
https://www.ncbi.nlm.nih.gov/pubmed/27841257
http://dx.doi.org/10.1038/ncomms13250

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