GR-independent down-modulation on GM-CSF bone marrow-derived dendritic cells by the selective glucocorticoid receptor modulator Compound A

Dendritic cells (DC) initiate the adaptive immune response. Glucocorticoids (GCs) down-modulate the function of DC. Compound A (CpdA, (2-(4-acetoxyphenyl)-2-chloro-N-methyl-ethylammonium chloride) is a plant-derived GR-ligand with marked dissociative properties. We investigated the effects of CpdA o...

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Detalles Bibliográficos
Autores principales: Barcala Tabarrozzi, Andres E., Andreone, Luz, Deckers, Julie, Castro, Carla N., Gimeno, María L., Ariolfo, Laura, Berguer, Paula M., Antunica-Noguerol, María, Liberman, Ana C., Vettorazzi, Sabine, Tuckermann, Jan P., De Bosscher, Karolien, Perone, Marcelo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114550/
https://www.ncbi.nlm.nih.gov/pubmed/27857212
http://dx.doi.org/10.1038/srep36646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114550/
https://www.ncbi.nlm.nih.gov/pubmed/27857212
http://dx.doi.org/10.1038/srep36646

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