STEP activation by Gαq coupled GPCRs opposes Src regulation of NMDA receptors containing the GluN2A subunit

N-methyl-D-aspartate receptors (NMDARs) are necessary for the induction of synaptic plasticity and for the consolidation of learning and memory. NMDAR function is tightly regulated by functionally opposed families of kinases and phosphatases. Herein we show that the striatal-enriched protein tyrosin...

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Detalles Bibliográficos
Autores principales: Tian, Meng, Xu, Jian, Lei, Gang, Lombroso, Paul J., Jackson, Michael F., MacDonald, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114553/
https://www.ncbi.nlm.nih.gov/pubmed/27857196
http://dx.doi.org/10.1038/srep36684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114553/
https://www.ncbi.nlm.nih.gov/pubmed/27857196
http://dx.doi.org/10.1038/srep36684

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