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Reader domain specificity and lysine demethylase-4 family function

The KDM4 histone demethylases are conserved epigenetic regulators linked to development, spermatogenesis and tumorigenesis. However, how the KDM4 family targets specific chromatin regions is largely unknown. Here, an extensive histone peptide microarray analysis uncovers trimethyl-lysine histone-bin...

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Detalles Bibliográficos
Autores principales: Su, Zhangli, Wang, Fengbin, Lee, Jin-Hee, Stephens, Kimberly E., Papazyan, Romeo, Voronina, Ekaterina, Krautkramer, Kimberly A., Raman, Ana, Thorpe, Jeremy J., Boersma, Melissa D., Kuznetsov, Vyacheslav I., Miller, Mitchell D., Taverna, Sean D., Phillips, George N., Denu, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114558/
https://www.ncbi.nlm.nih.gov/pubmed/27841353
http://dx.doi.org/10.1038/ncomms13387