Cargando…

Regulation of persistent sodium currents by glycogen synthase kinase 3 encodes daily rhythms of neuronal excitability

How neurons encode intracellular biochemical signalling cascades into electrical signals is not fully understood. Neurons in the central circadian clock in mammals provide a model system to investigate electrical encoding of biochemical timing signals. Here, using experimental and modelling approach...

Descripción completa

Detalles Bibliográficos
Autores principales: Paul, Jodi R., DeWoskin, Daniel, McMeekin, Laura J., Cowell, Rita M., Forger, Daniel B., Gamble, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114562/
https://www.ncbi.nlm.nih.gov/pubmed/27841351
http://dx.doi.org/10.1038/ncomms13470