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Principles of proteome allocation are revealed using proteomic data and genome-scale models

Integrating omics data to refine or make context-specific models is an active field of constraint-based modeling. Proteomics now cover over 95% of the Escherichia coli proteome by mass. Genome-scale models of Metabolism and macromolecular Expression (ME) compute proteome allocation linked to metabol...

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Detalles Bibliográficos
Autores principales: Yang, Laurence, Yurkovich, James T., Lloyd, Colton J., Ebrahim, Ali, Saunders, Michael A., Palsson, Bernhard O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114563/
https://www.ncbi.nlm.nih.gov/pubmed/27857205
http://dx.doi.org/10.1038/srep36734