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Deregulation of the miR-16-KRAS axis promotes colorectal cancer

KRAS plays a significant role in the etiology and progression of colorectal cancer (CRC), but the mechanism underlying this process has not been fully elucidated. In this study, we found that the KRAS protein levels were higher in CRC tissues than in the normal adjacent tissues, whereas its mRNA lev...

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Detalles Bibliográficos
Autores principales: You, Chaoying, Liang, Hongwei, Sun, Wu, Li, Jialu, Liu, Yanqing, Fan, Qian, Zhang, Haiyang, Yue, Xin, Li, Jing, Chen, Xi, Ba, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114589/
https://www.ncbi.nlm.nih.gov/pubmed/27857191
http://dx.doi.org/10.1038/srep37459