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Hierarchical zwitterionic modification of a SERS substrate enables real-time drug monitoring in blood plasma

Surface-enhanced Raman spectroscopy (SERS) is an ultrasensitive analytical technique with molecular specificity, making it an ideal candidate for therapeutic drug monitoring (TDM). However, in critical diagnostic media including blood, nonspecific protein adsorption coupled with weak surface affinit...

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Detalles Bibliográficos
Autores principales: Sun, Fang, Hung, Hsiang-Chieh, Sinclair, Andrew, Zhang, Peng, Bai, Tao, Galvan, Daniel David, Jain, Priyesh, Li, Bowen, Jiang, Shaoyi, Yu, Qiuming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114600/
https://www.ncbi.nlm.nih.gov/pubmed/27834380
http://dx.doi.org/10.1038/ncomms13437