Exercise reverses age‐related vulnerability of the retina to injury by preventing complement‐mediated synapse elimination via a BDNF‐dependent pathway

Retinal ganglion cells (RGCs) become increasingly vulnerable to injury with advancing age. We recently showed that this vulnerability can be strongly modified in mice by exercise. However, the characteristics and underlying mechanisms of retinal protection with exercise remain unknown. Hence, the ai...

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Detalles Bibliográficos
Autores principales: Chrysostomou, Vicki, Galic, Sandra, van Wijngaarden, Peter, Trounce, Ian A., Steinberg, Gregory R., Crowston, Jonathan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114604/
https://www.ncbi.nlm.nih.gov/pubmed/27613664
http://dx.doi.org/10.1111/acel.12512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114604/
https://www.ncbi.nlm.nih.gov/pubmed/27613664
http://dx.doi.org/10.1111/acel.12512

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