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Exercise reverses age‐related vulnerability of the retina to injury by preventing complement‐mediated synapse elimination via a BDNF‐dependent pathway
Retinal ganglion cells (RGCs) become increasingly vulnerable to injury with advancing age. We recently showed that this vulnerability can be strongly modified in mice by exercise. However, the characteristics and underlying mechanisms of retinal protection with exercise remain unknown. Hence, the ai...
Autores principales: | Chrysostomou, Vicki, Galic, Sandra, van Wijngaarden, Peter, Trounce, Ian A., Steinberg, Gregory R., Crowston, Jonathan G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114604/ https://www.ncbi.nlm.nih.gov/pubmed/27613664 http://dx.doi.org/10.1111/acel.12512 |
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