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YY1 binding association with sex-biased transcription revealed through X-linked transcript levels and allelic binding analyses

Sex differences in susceptibility and progression have been reported in numerous diseases. Female cells have two copies of the X chromosome with X-chromosome inactivation imparting mono-allelic gene silencing for dosage compensation. However, a subset of genes, named escapees, escape silencing and a...

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Detalles Bibliográficos
Autores principales: Chen, Chih-yu, Shi, Wenqiang, Balaton, Bradley P., Matthews, Allison M., Li, Yifeng, Arenillas, David J., Mathelier, Anthony, Itoh, Masayoshi, Kawaji, Hideya, Lassmann, Timo, Hayashizaki, Yoshihide, Carninci, Piero, Forrest, Alistair R. R., Brown, Carolyn J., Wasserman, Wyeth W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114649/
https://www.ncbi.nlm.nih.gov/pubmed/27857184
http://dx.doi.org/10.1038/srep37324