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YY1 binding association with sex-biased transcription revealed through X-linked transcript levels and allelic binding analyses
Sex differences in susceptibility and progression have been reported in numerous diseases. Female cells have two copies of the X chromosome with X-chromosome inactivation imparting mono-allelic gene silencing for dosage compensation. However, a subset of genes, named escapees, escape silencing and a...
Autores principales: | Chen, Chih-yu, Shi, Wenqiang, Balaton, Bradley P., Matthews, Allison M., Li, Yifeng, Arenillas, David J., Mathelier, Anthony, Itoh, Masayoshi, Kawaji, Hideya, Lassmann, Timo, Hayashizaki, Yoshihide, Carninci, Piero, Forrest, Alistair R. R., Brown, Carolyn J., Wasserman, Wyeth W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114649/ https://www.ncbi.nlm.nih.gov/pubmed/27857184 http://dx.doi.org/10.1038/srep37324 |
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