Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy

Photodynamic therapy (PDT) and diagnosis (PDD) using 5-aminolevulinic acid (ALA) to drive the production of an intracellular photosensitizer, protoporphyrin IX (PpIX), are in common clinical use. However, the tendency to accumulate PpIX is not well understood. Patients with cancer can develop recurr...

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Detalles Bibliográficos
Autores principales: Nakayama, Taku, Otsuka, Shimpei, Kobayashi, Tatsuya, Okajima, Hodaka, Matsumoto, Kentaro, Hagiya, Yuichiro, Inoue, Keiji, Shuin, Taro, Nakajima, Motowo, Tanaka, Tohru, Ogura, Shun-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114660/
https://www.ncbi.nlm.nih.gov/pubmed/27857072
http://dx.doi.org/10.1038/srep36478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114660/
https://www.ncbi.nlm.nih.gov/pubmed/27857072
http://dx.doi.org/10.1038/srep36478

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