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The Modification of Tet1 in Male Germline Stem Cells and Interact with PCNA, HDAC1 to promote their Self-renewal and Proliferation

Epigenetic modification plays key roles in spermatogenesis, especially DNA methylation dynamic is important in sustaining normal spermatogenesis. Ten-eleven translocation 1 (Tet1) is not only a key demethylase, which works in specific gene regions, but also crosstalks with partners to regulate epige...

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Detalles Bibliográficos
Autores principales: Zheng, Liming, Zhai, Yuanxin, Li, Na, Ma, Fanglin, Zhu, Haijing, Du, Xiaomin, Li, Guangpeng, Hua, Jinlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114665/
https://www.ncbi.nlm.nih.gov/pubmed/27857213
http://dx.doi.org/10.1038/srep37414