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LUC7L3/CROP inhibits replication of hepatitis B virus via suppressing enhancer II/basal core promoter activity

The core promoter of hepatitis B virus (HBV) genome is a critical region for transcriptional initiation of 3.5 kb, pregenome and precore RNAs and for the viral replication. Although a number of host-cell factors that potentially regulate the viral promoter activities have been identified, the molecu...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Ito, Masahiko, Sun, Suofeng, Chida, Takeshi, Nakashima, Kenji, Suzuki, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114668/
https://www.ncbi.nlm.nih.gov/pubmed/27857158
http://dx.doi.org/10.1038/srep36741