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Endotoxemia contributes to CD27+ memory B-cell apoptosis via enhanced sensitivity to Fas ligation in patients with Cirrhosis

Peripheral CD27(+) memory B-cells become quantitatively reduced and dysfunctional in patients with cirrhosis through poorly characterized mechanisms. We hypothesized that the disappearance of CD27(+) memory B-cells results from enhanced sensitivity to apoptosis caused by exposure to gut microbial tr...

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Detalles Bibliográficos
Autores principales: Chang, Li-Yuan, Li, Yonghai, Kaplan, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114671/
https://www.ncbi.nlm.nih.gov/pubmed/27857173
http://dx.doi.org/10.1038/srep36862