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Endotoxemia contributes to CD27+ memory B-cell apoptosis via enhanced sensitivity to Fas ligation in patients with Cirrhosis
Peripheral CD27(+) memory B-cells become quantitatively reduced and dysfunctional in patients with cirrhosis through poorly characterized mechanisms. We hypothesized that the disappearance of CD27(+) memory B-cells results from enhanced sensitivity to apoptosis caused by exposure to gut microbial tr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114671/ https://www.ncbi.nlm.nih.gov/pubmed/27857173 http://dx.doi.org/10.1038/srep36862 |