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Synthesis of (3R)-acetoin and 2,3-butanediol isomers by metabolically engineered Lactococcus lactis

The potential that lies in harnessing the chemical synthesis capabilities inherent in living organisms is immense. Here we demonstrate how the biosynthetic machinery of Lactococcus lactis, can be diverted to make (3R)-acetoin and the derived 2,3-butanediol isomers meso-(2,3)-butanediol (m-BDO) and (...

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Detalles Bibliográficos
Autores principales: Kandasamy, Vijayalakshmi, Liu, Jianming, Dantoft, Shruti Harnal, Solem, Christian, Jensen, Peter Ruhdal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114678/
https://www.ncbi.nlm.nih.gov/pubmed/27857195
http://dx.doi.org/10.1038/srep36769