Development of a population pharmacokinetic model of prucalopride in children with functional constipation

A recent phase 3 trial of prucalopride in children with functional constipation (SPD555‐303 ClinicalTrials.gov Identifier: NCT01330381) reported negative efficacy results. Here, we developed a population pharmacokinetic (PK) model of prucalopride in children to assess prucalopride exposure in SPD555...

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Detalles Bibliográficos
Autores principales: van Schaick, Erno, Benninga, Marc A., Levine, Amy, Magnusson, Mats, Troy, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114692/
https://www.ncbi.nlm.nih.gov/pubmed/27891230
http://dx.doi.org/10.1002/prp2.236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114692/
https://www.ncbi.nlm.nih.gov/pubmed/27891230
http://dx.doi.org/10.1002/prp2.236

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