Reducing translation through eIF4G/IFG‐1 improves survival under ER stress that depends on heat shock factor HSF‐1 in Caenorhabditis elegans

Although certain methods of lowering and/or altering mRNA translation are associated with increased lifespan, the mechanisms underlying this effect remain largely unknown. We previously showed that the increased lifespan conferred by reducing expression of eukaryotic translation initiation factor 4G...

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Detalles Bibliográficos
Autores principales: Howard, Amber C., Rollins, Jarod, Snow, Santina, Castor, Sarah, Rogers, Aric N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114698/
https://www.ncbi.nlm.nih.gov/pubmed/27538368
http://dx.doi.org/10.1111/acel.12516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114698/
https://www.ncbi.nlm.nih.gov/pubmed/27538368
http://dx.doi.org/10.1111/acel.12516

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