Biological characterization of chemically diverse compounds targeting the Plasmodium falciparum coenzyme A synthesis pathway

BACKGROUND: In the fight against malaria, the discovery of chemical compounds with a novel mode of action and/or chemistry distinct from currently used drugs is vital to counteract the parasite’s known ability to develop drug resistance. Another desirable aspect is efficacy against gametocytes, the...

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Detalles Bibliográficos
Autores principales: Fletcher, Sabine, Lucantoni, Leonardo, Sykes, Melissa L., Jones, Amy J., Holleran, John P., Saliba, Kevin J., Avery, Vicky M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114727/
https://www.ncbi.nlm.nih.gov/pubmed/27855724
http://dx.doi.org/10.1186/s13071-016-1860-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114727/
https://www.ncbi.nlm.nih.gov/pubmed/27855724
http://dx.doi.org/10.1186/s13071-016-1860-3

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