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Biological characterization of chemically diverse compounds targeting the Plasmodium falciparum coenzyme A synthesis pathway
BACKGROUND: In the fight against malaria, the discovery of chemical compounds with a novel mode of action and/or chemistry distinct from currently used drugs is vital to counteract the parasite’s known ability to develop drug resistance. Another desirable aspect is efficacy against gametocytes, the...
Autores principales: | Fletcher, Sabine, Lucantoni, Leonardo, Sykes, Melissa L., Jones, Amy J., Holleran, John P., Saliba, Kevin J., Avery, Vicky M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114727/ https://www.ncbi.nlm.nih.gov/pubmed/27855724 http://dx.doi.org/10.1186/s13071-016-1860-3 |
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