Laddar…
CD274 promotes cell cycle entry of leukemia-initiating cells through JNK/Cyclin D2 signaling
BACKGROUND: CD274 (programmed death ligand 1, also known as B7H1) is expressed in both solid tumors and hematologic malignancies and is of critical importance for the escape of tumor cells from immune surveillance by inhibiting T cell function via its receptor, programmed death 1 (PD-1). Increasing...
Huvudupphovsmän: | , , , , , , , , , , , , , , |
---|---|
Materialtyp: | Online Artikel Text |
Språk: | English |
Publicerad: |
BioMed Central
2016
|
Ämnen: | |
Länkar: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114730/ https://www.ncbi.nlm.nih.gov/pubmed/27855694 http://dx.doi.org/10.1186/s13045-016-0350-6 |