CD274 promotes cell cycle entry of leukemia-initiating cells through JNK/Cyclin D2 signaling

BACKGROUND: CD274 (programmed death ligand 1, also known as B7H1) is expressed in both solid tumors and hematologic malignancies and is of critical importance for the escape of tumor cells from immune surveillance by inhibiting T cell function via its receptor, programmed death 1 (PD-1). Increasing...

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Detalles Bibliográficos
Autores principales: Fang, Xia, Chen, Chiqi, Xia, Fangzhen, Yu, Zhuo, Zhang, Yaping, Zhang, Feifei, Gu, Hao, Wan, Jiangbo, Zhang, Xiaocui, Weng, Wei, Zhang, Cheng Cheng, Chen, Guo-Qiang, Liang, Aibing, Xie, Li, Zheng, Junke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114730/
https://www.ncbi.nlm.nih.gov/pubmed/27855694
http://dx.doi.org/10.1186/s13045-016-0350-6

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