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Genetic dissection of the fatty liver QTL Fl1sa by using congenic mice and identification of candidate genes in the liver and epididymal fat

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a multifactorial disease caused by interactions between environmental and genetic factors. The SMXA-5 mouse is a high-fat diet-induced fatty liver model established from SM/J and A/J strains. We have previously identified Fl1sa, a quantitative...

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Detalles Bibliográficos
Autores principales: Suzuki, Miyako, Kobayashi, Misato, Ohno, Tamio, Kanamori, Shinsaku, Tateishi, Soushi, Murai, Atsushi, Horio, Fumihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114839/
https://www.ncbi.nlm.nih.gov/pubmed/27855657
http://dx.doi.org/10.1186/s12863-016-0453-7