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Genetic dissection of the fatty liver QTL Fl1sa by using congenic mice and identification of candidate genes in the liver and epididymal fat
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a multifactorial disease caused by interactions between environmental and genetic factors. The SMXA-5 mouse is a high-fat diet-induced fatty liver model established from SM/J and A/J strains. We have previously identified Fl1sa, a quantitative...
Autores principales: | Suzuki, Miyako, Kobayashi, Misato, Ohno, Tamio, Kanamori, Shinsaku, Tateishi, Soushi, Murai, Atsushi, Horio, Fumihiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114839/ https://www.ncbi.nlm.nih.gov/pubmed/27855657 http://dx.doi.org/10.1186/s12863-016-0453-7 |
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