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Eomes(hi) NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation

Human liver contains an Eomes(hi) population of NK cells that is not present in the blood. In this study, we show that these cells are characterized by a molecular signature that mediates their retention in the liver. By examining liver transplants where donors and recipients are HLA mismatched, we...

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Detalles Bibliográficos
Autores principales: Cuff, Antonia O., Robertson, Francis P., Stegmann, Kerstin A., Pallett, Laura J., Maini, Mala K., Davidson, Brian R., Male, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114885/
https://www.ncbi.nlm.nih.gov/pubmed/27798170
http://dx.doi.org/10.4049/jimmunol.1601424