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The Effect of Garlic Derivatives (S-Allylmercaptocysteine, Diallyl Disulfide, and S-Allylcysteine) on Gentamicin Induced Ototoxicity: An Experimental Study

OBJECTIVES: Gentamicin is a potent aminoglycoside antibiotic. Ototoxicity and nephrotoxicity are the main side effects which restrict the use of gentamicin. Garlic with its intrinsic antioxidant activity may prove beneficial in prevention from ototoxicity. S-allylmercaptocysteine (SAMC), diallyl dis...

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Detalles Bibliográficos
Autores principales: Uzun, Lokman, Kokten, Numan, Cam, Osman Halit, Kalcioglu, M.Tayyar, Ugur, M. Birol, Tekin, Muhammet, Acar, Gul Ozbilen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115152/
https://www.ncbi.nlm.nih.gov/pubmed/27136366
http://dx.doi.org/10.21053/ceo.2015.01032