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Identification of CETP as a molecular target for estrogen positive breast cancer cell death by cholesterol depleting agents

Cholesterol and its metabolites act as steroid hormone precursors, which promote estrogen receptor positive (ER+) breast cancer (BC) progression. Development of cholesterol targeting anticancer drugs has been hindered due to the lack of knowledge of viable molecular targets. Till now, Cholesteryl es...

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Detalles Bibliográficos
Autores principales: Esau, Luke, Sagar, Sunil, Bangarusamy, Dhinoth, Kaur, Mandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115172/
https://www.ncbi.nlm.nih.gov/pubmed/28050232
http://dx.doi.org/10.18632/genesandcancer.122