Cargando…

Identification of CETP as a molecular target for estrogen positive breast cancer cell death by cholesterol depleting agents

Cholesterol and its metabolites act as steroid hormone precursors, which promote estrogen receptor positive (ER+) breast cancer (BC) progression. Development of cholesterol targeting anticancer drugs has been hindered due to the lack of knowledge of viable molecular targets. Till now, Cholesteryl es...

Descripción completa

Detalles Bibliográficos
Autores principales:	Esau, Luke, Sagar, Sunil, Bangarusamy, Dhinoth, Kaur, Mandeep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115172/ https://www.ncbi.nlm.nih.gov/pubmed/28050232 http://dx.doi.org/10.18632/genesandcancer.122

Ejemplares similares

Cytotoxicity and Apoptosis Induced by a Plumbagin Derivative in Estrogen Positive MCF-7 Breast Cancer Cells
por: Sagar, Sunil, et al.
Publicado: (2014)

Xanthohumol Prevents Atherosclerosis by Reducing Arterial Cholesterol Content via CETP and Apolipoprotein E in CETP-Transgenic Mice
por: Hirata, Hiroshi, et al.
Publicado: (2012)

Variants in the CETP gene affect levels of HDL cholesterol by reducing the amount, and not the specific lipid transfer activity, of secreted CETP
por: Ølnes, Åsa Schawlann, et al.
Publicado: (2023)

Mining the deep Red-Sea brine pool microbial community for anticancer therapeutics
por: Esau, Luke, et al.
Publicado: (2019)

The cholesteryl ester transfer protein (CETP) raises cholesterol levels in the brain
por: Oestereich, Felix, et al.
Publicado: (2022)

Cholesteryl Ester Transfer Protein (CETP) Deficiency and CETP Inhibitors
por: Mabuchi, Hiroshi, et al.
Publicado: (2014)

Can the Salivary Microbiome Predict Cardiovascular Diseases? Lessons Learned From the Qatari Population
por: Murugesan, Selvasankar, et al.
Publicado: (2021)

The Association of Common SNPs and Haplotypes in CETP Gene with HDL Cholesterol Levels in Latvian Population
por: Radovica, Ilze, et al.
Publicado: (2013)

Cytotoxic and apoptotic evaluations of marine bacteria isolated from brine-seawater interface of the Red Sea
por: Sagar, Sunil, et al.
Publicado: (2013)

Induction of apoptosis in cancer cell lines by the Red Sea brine pool bacterial extracts
por: Sagar, Sunil, et al.
Publicado: (2013)

Segregation of LIPG, CETP, and GALNT2 Mutations in Caucasian Families with Extremely High HDL Cholesterol
por: Tietjen, Ian, et al.
Publicado: (2012)

The lipid substrate preference of CETP controls the biochemical properties of HDL in fat/cholesterol-fed hamsters
por: Morton, Richard E., et al.
Publicado: (2021)

CETP, LIPC, and SCARB1 variants in individuals with extremely high high-density lipoprotein-cholesterol levels
por: Lee, Chan Joo, et al.
Publicado: (2019)

Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer
por: Simigdala, Nikiana, et al.
Publicado: (2016)

Increased Relative Abundance of Ruminoccocus Is Associated With Reduced Cardiovascular Risk in an Obese Population
por: Lakshmanan, Arun Prasath, et al.
Publicado: (2022)

Niacin Reduces Atherosclerosis Development in APOE*3Leiden.CETP Mice Mainly by Reducing NonHDL-Cholesterol
por: Kühnast, Susan, et al.
Publicado: (2013)

Exercise Training Favorably Modulates Gene and Protein Expression That Regulate Arterial Cholesterol Content in CETP Transgenic Mice
por: Pinto, Paula R., et al.
Publicado: (2018)

Targeted transcriptional repression using a chimeric TALE-SRDX repressor protein
por: Mahfouz, Magdy M., et al.
Publicado: (2011)

Proteogenomic Approaches for the Identification of NF1/Neurofibromin-depleted Estrogen Receptor–positive Breast Cancers for Targeted Treatment
por: Kim, Beom-Jun, et al.
Publicado: (2023)

Association studies of several cholesterol-related genes (ABCA1, CETP and LIPC) with serum lipids and risk of Alzheimer’s disease
por: Xiao, Zhijie, et al.
Publicado: (2012)

Impact of variants in CETP and apo AI genes on serum HDL cholesterol levels in men and women from the Polish population
por: Włodarczyk, Marta, et al.
Publicado: (2016)

Discovery of estrogen receptor α target genes and response elements in breast tumor cells
por: Lin, Chin-Yo, et al.
Publicado: (2004)

Editorial: Cholesterol and cancer drug resistance: Molecular, signaling, and therapeutic aspects
por: Kaur, Mandeep, et al.
Publicado: (2022)

CETP Inhibition: Past Failures and Future Hopes
por: Kosmas, Constantine E., et al.
Publicado: (2016)

A reduction of CETP activity, not an increase, is associated with modestly impaired postprandial lipemia and increased HDL-Cholesterol in adult asymptomatic women
por: Parra, Eliane S, et al.
Publicado: (2011)

A Vaccine Targeted at CETP Alleviates High Fat and High Cholesterol Diet-Induced Atherosclerosis and Non-Alcoholic Steatohepatitis in Rabbit
por: Liaw, Yi-Wei, et al.
Publicado: (2014)

Cholesteryl ester transfer protein (CETP), HDL capacity of receiving cholesterol and status of inflammatory cytokines in patients with severe heart failure
por: Martinelli, Ana Elisa M., et al.
Publicado: (2018)

The effect of the association between CETP variant type and alcohol consumption on cholesterol level differs according to the ALDH2 variant type
por: Yoo, Min-Gyu, et al.
Publicado: (2022)

Cholesteryl Ester Transfer Protein (CETP) expression does not affect glucose homeostasis and insulin secretion: studies in human CETP transgenic mice
por: Raposo, Helena F., et al.
Publicado: (2016)

CETP inhibitors and cardiovascular disease: Time to think again
por: Miller, Norman E
Publicado: (2014)

Prevention of fatal hepatic complication in schistosomiasis by inhibition of CETP
por: Yokoyama, Shinji, et al.
Publicado: (2015)

Genetic variants in CETP increase risk of intracerebral hemorrhage
por: Anderson, Christopher D., et al.
Publicado: (2016)

Association of CETP Gene Polymorphisms and Haplotypes with Cardiovascular Risk
por: Piko, Peter, et al.
Publicado: (2023)

CETP inhibitor evacetrapib enters mouse brain tissue
por: Phénix, Jasmine, et al.
Publicado: (2023)

CETP Inhibition Improves HDL Function but Leads to Fatty Liver and Insulin Resistance in CETP-Expressing Transgenic Mice on a High-Fat Diet
por: Zhu, Lin, et al.
Publicado: (2018)

Cholesterol ester transfer protein (CETP) gene polymorphism and selected parameters of lipid metabolism in children from families with history of cardiovascular system diseases
por: Pac-Kożuchowska, Elżbieta, et al.
Publicado: (2013)

eNOS Activation by HDL Is Impaired in Genetic CETP Deficiency
por: Gomaraschi, Monica, et al.
Publicado: (2014)

CETP inhibition in the REVEAL trial: could we aim higher?
por: Sahebkar, Amirhossein, et al.
Publicado: (2020)

Cholesterol synthesis inhibition or depletion in axon regeneration
por: Tang, Bor Luen
Publicado: (2021)

A Systems Analysis of Phenotype Heterogeneity in APOE*3Leiden.CETP Mice Induced by Long-Term High-Fat High-Cholesterol Diet Feeding
por: Paalvast, Yared, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_h9k2i87sq64t1e3vp5aega343f