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Oxidative Stress: 1,5‐Diazacyclooctanes, as Exclusive Oxidative Polyamine Metabolites, Inhibit Amyloid‐β(1‐40) Fibrillization (Adv. Sci. 10/2016)

The level of expression of polyamines and a highly reactive and toxic acrolein, has been linked to the progression of certain neurodenerative diseases such as Alzheimer's disease. But now the story has become more complex. Katsunori Tanaka and co‐workers discover that 1,5‐diazacyclooctanes cons...

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Detalles Bibliográficos
Autores principales: Tsutsui, Ayumi, Zako, Tamotsu, Bu, Tong, Yamaguchi, Yoshiki, Maeda, Mizuo, Tanaka, Katsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115592/
http://dx.doi.org/10.1002/advs.201670055