Heterogeneous Uptake of Nanoparticles in Mouse Models of Pediatric High-Risk Neuroblastoma

Liposomal chemotherapeutics are exemplified by DOXIL® are commonly used in adult cancers. While these agents exhibit improved safety profile compared to their free drug counterparts, their treatment response rates have been ~ 20%, often attributed to the heterogeneous intratumoral uptake and distrib...

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Detalles Bibliográficos
Autores principales: Ghaghada, Ketan B., Starosolski, Zbigniew A., Lakoma, Anna, Kaffes, Caterina, Agarwal, Saurabh, Athreya, Khannan K., Shohet, Jason, Kim, Eugene, Annapragada, Ananth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115667/
https://www.ncbi.nlm.nih.gov/pubmed/27861510
http://dx.doi.org/10.1371/journal.pone.0165877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115667/
https://www.ncbi.nlm.nih.gov/pubmed/27861510
http://dx.doi.org/10.1371/journal.pone.0165877

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