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Preparation and characterization of novel chitosan–protamine nanoparticles for nucleus-targeted anticancer drug delivery
It is well known that most anticancer drugs commonly show high toxicity to the DNA of tumor cells and exert effects by combining with the DNA or associated enzymes in the nucleus. Most developed drugs are first delivered into the cytoplasm and then transferred to the nucleus through the membrane por...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115688/ https://www.ncbi.nlm.nih.gov/pubmed/27881917 http://dx.doi.org/10.2147/IJN.S117066 |