Development and Validation of a New Mouse Model to Investigate the Role of SV2A in Epilepsy

SV2A is a glycoprotein present in the membranes of most synaptic vesicles. Although it has been highly conserved throughout evolution, its physiological role remains largely unknown. Nevertheless, Levetiracetam, a very effective anti-epileptic drug, has been recently demonstrated to bind to SV2A. At...

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Detalles Bibliográficos
Autores principales: Menten-Dedoyart, Catherine, Serrano Navacerrada, Maria Elisa, Bartholome, Odile, Sánchez Gil, Judit, Neirinckx, Virginie, Wislet, Sabine, Becker, Guillaume, Plenevaux, Alain, Van den Ackerveken, Priscilla, Rogister, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115750/
https://www.ncbi.nlm.nih.gov/pubmed/27861538
http://dx.doi.org/10.1371/journal.pone.0166525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115750/
https://www.ncbi.nlm.nih.gov/pubmed/27861538
http://dx.doi.org/10.1371/journal.pone.0166525

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