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Pdcd2l Promotes Palmitate-Induced Pancreatic Beta-Cell Apoptosis as a FoxO1 Target Gene

Transcription factor FoxO1 is a key regulator of the insulin-signaling pathway, and is reported to play important roles in pancreatic β cell differentiation, proliferation, apoptosis and stress resistance. The multifunctional nature of FoxO1 is due to its regulation of various downstream targets. Pr...

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Detalles Bibliográficos
Autores principales: Yin, Ye, Yong, Wei, Yu, Jiani, Zhang, Xu, Lin, Haiyan, Zhu, Yunxia, Han, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115776/
https://www.ncbi.nlm.nih.gov/pubmed/27861641
http://dx.doi.org/10.1371/journal.pone.0166692