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Propagated but Topologically Distributed Forebrain Neurons Expressing Alpha-Synuclein in Aged Macaques
In neurodegenerative disorders, such as Parkinson's disease (PD), alpha-synuclein (α-syn) accumulates to induce cell death and/or form a cytoplasmic inclusion called Lewy body (LB). This α-syn-related pathology is termed synucleinopathy. It remains unclear how α-syn accumulation expands during...
Autores principales: | Kimura, Katsuo, Inoue, Ken-ichi, Kuroiwa, Yoshiyuki, Tanaka, Fumiaki, Takada, Masahiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115821/ https://www.ncbi.nlm.nih.gov/pubmed/27861638 http://dx.doi.org/10.1371/journal.pone.0166861 |
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