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The Expression of the Endogenous mTORC1 Inhibitor Sestrin 2 Is Induced by UVB and Balanced with the Expression Level of Sestrin 1

Sestrin 2 (SESN2) is an evolutionarily conserved regulator of mechanistic target of rapamycin complex 1 (mTORC1) which controls central cellular processes such as protein translation and autophagy. Previous studies have suggested that SESN2 itself is subjected to regulation at multiple levels. Here,...

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Detalles Bibliográficos
Autores principales: Mlitz, Veronika, Gendronneau, Gaelle, Berlin, Irina, Buchberger, Maria, Eckhart, Leopold, Tschachler, Erwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115827/
https://www.ncbi.nlm.nih.gov/pubmed/27861561
http://dx.doi.org/10.1371/journal.pone.0166832