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Identifying Causal Genes at the Multiple Sclerosis Associated Region 6q23 Using Capture Hi-C

BACKGROUND: The chromosomal region 6q23 has been found to be associated with multiple sclerosis (MS) predisposition through genome wide association studies (GWAS). There are four independent single nucleotide polymorphisms (SNPs) associated with MS in this region, which spans around 2.5 Mb. Most GWA...

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Detalles Bibliográficos
Autores principales: Martin, Paul, McGovern, Amanda, Massey, Jonathan, Schoenfelder, Stefan, Duffus, Kate, Yarwood, Annie, Barton, Anne, Worthington, Jane, Fraser, Peter, Eyre, Stephen, Orozco, Gisela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115837/
https://www.ncbi.nlm.nih.gov/pubmed/27861577
http://dx.doi.org/10.1371/journal.pone.0166923