HMGA2 Moderately Increases Fetal Hemoglobin Expression in Human Adult Erythroblasts

Induction of fetal hemoglobin (HbF) has therapeutic importance for patients with beta-hemoglobin disorders. Previous studies showed that let-7 microRNAs (miRNAs) are highly regulated in erythroid cells during the fetal-to-adult developmental transition, and that targeting let-7 mediated the up-regul...

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Detalles Bibliográficos
Autores principales: de Vasconcellos, Jaira F., Lee, Y. Terry, Byrnes, Colleen, Tumburu, Laxminath, Rabel, Antoinette, Miller, Jeffery L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115839/
https://www.ncbi.nlm.nih.gov/pubmed/27861570
http://dx.doi.org/10.1371/journal.pone.0166928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115839/
https://www.ncbi.nlm.nih.gov/pubmed/27861570
http://dx.doi.org/10.1371/journal.pone.0166928

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