Long-Range Control of Renin Gene Expression in Tsukuba Hypertensive Mice

Renin, a rate-limiting enzyme in the renin–angiotensin system, is regulated to maintain blood pressure homeostasis: renin gene expression in the kidney is suppressed in a hypertensive environment. We found that expression of a 15-kb human RENIN (hREN) transgene was aberrantly upregulated (>4.2-fo...

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Detalles Bibliográficos
Autores principales: Ushiki, Aki, Matsuzaki, Hitomi, Ishida, Junji, Fukamizu, Akiyoshi, Tanimoto, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115840/
https://www.ncbi.nlm.nih.gov/pubmed/27861631
http://dx.doi.org/10.1371/journal.pone.0166974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115840/
https://www.ncbi.nlm.nih.gov/pubmed/27861631
http://dx.doi.org/10.1371/journal.pone.0166974

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