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Computational Identification of Tissue-Specific Splicing Regulatory Elements in Human Genes from RNA-Seq Data

Alternative splicing is a vital process for regulating gene expression and promoting proteomic diversity. It plays a key role in tissue-specific expressed genes. This specificity is mainly regulated by splicing factors that bind to specific sequences called splicing regulatory elements (SREs). Here,...

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Detalles Bibliográficos
Autores principales: Badr, Eman, ElHefnawi, Mahmoud, Heath, Lenwood S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115852/
https://www.ncbi.nlm.nih.gov/pubmed/27861625
http://dx.doi.org/10.1371/journal.pone.0166978