Structure and dynamics underlying elementary ligand binding events in human pacemaking channels

Although molecular recognition is crucial for cellular signaling, mechanistic studies have relied primarily on ensemble measures that average over and thereby obscure underlying steps. Single-molecule observations that resolve these steps are lacking due to diffraction-limited resolution of single f...

Descripción completa

Detalles Bibliográficos
Autores principales: Goldschen-Ohm, Marcel P, Klenchin, Vadim A, White, David S, Cowgill, John B, Cui, Qiang, Goldsmith, Randall H, Chanda, Baron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115869/
https://www.ncbi.nlm.nih.gov/pubmed/27858593
http://dx.doi.org/10.7554/eLife.20797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115869/
https://www.ncbi.nlm.nih.gov/pubmed/27858593
http://dx.doi.org/10.7554/eLife.20797

Ejemplares similares