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Structural determinants of adhesion by Protocadherin-19 and implications for its role in epilepsy

Non-clustered δ-protocadherins are homophilic cell adhesion molecules essential for the development of the vertebrate nervous system, as several are closely linked to neurodevelopmental disorders. Mutations in protocadherin-19 (PCDH19) result in a female-limited, infant-onset form of epilepsy (PCDH1...

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Detalles Bibliográficos
Autores principales: Cooper, Sharon R, Jontes, James D, Sotomayor, Marcos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115871/
https://www.ncbi.nlm.nih.gov/pubmed/27787195
http://dx.doi.org/10.7554/eLife.18529