Cargando…
Structural determinants of adhesion by Protocadherin-19 and implications for its role in epilepsy
Non-clustered δ-protocadherins are homophilic cell adhesion molecules essential for the development of the vertebrate nervous system, as several are closely linked to neurodevelopmental disorders. Mutations in protocadherin-19 (PCDH19) result in a female-limited, infant-onset form of epilepsy (PCDH1...
Autores principales: | Cooper, Sharon R, Jontes, James D, Sotomayor, Marcos |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115871/ https://www.ncbi.nlm.nih.gov/pubmed/27787195 http://dx.doi.org/10.7554/eLife.18529 |
Ejemplares similares
-
γ-Protocadherin structural diversity and functional implications
por: Goodman, Kerry Marie, et al.
Publicado: (2016) -
Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5
por: Ge, Jingpeng, et al.
Publicado: (2018) -
Antiparallel protocadherin homodimers use distinct affinity- and specificity-mediating regions in cadherin repeats 1-4
por: Nicoludis, John M, et al.
Publicado: (2016) -
Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly
por: Cottee, Matthew A, et al.
Publicado: (2013) -
Structure of bacterial cytoplasmic chemoreceptor arrays and implications for chemotactic signaling
por: Briegel, Ariane, et al.
Publicado: (2014)