Transgenic expression of cyclooxygenase-2 (COX2) causes premature aging phenotypes in mice

Cyclooxygenase (COX) is a key enzyme in the biosynthesis of prostanoids, lipid signaling molecules that regulate various physiological processes. COX2, one of the isoforms of COX, is highly inducible in response to a wide variety of cellular and environmental stresses. Increased COX2 expression is t...

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Detalles Bibliográficos
Autores principales: Kim, Joohwee, Vaish, Vivek, Feng, Mingxiao, Field, Kevin, Chatzistamou, Ioulia, Shim, Minsub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115895/
https://www.ncbi.nlm.nih.gov/pubmed/27750221
http://dx.doi.org/10.18632/aging.101060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115895/
https://www.ncbi.nlm.nih.gov/pubmed/27750221
http://dx.doi.org/10.18632/aging.101060

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