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Transgenic expression of cyclooxygenase-2 (COX2) causes premature aging phenotypes in mice
Cyclooxygenase (COX) is a key enzyme in the biosynthesis of prostanoids, lipid signaling molecules that regulate various physiological processes. COX2, one of the isoforms of COX, is highly inducible in response to a wide variety of cellular and environmental stresses. Increased COX2 expression is t...
Autores principales: | Kim, Joohwee, Vaish, Vivek, Feng, Mingxiao, Field, Kevin, Chatzistamou, Ioulia, Shim, Minsub |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115895/ https://www.ncbi.nlm.nih.gov/pubmed/27750221 http://dx.doi.org/10.18632/aging.101060 |
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