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Lower circulating insulin-like growth factor-I is associated with better cognition in females with exceptional Longevity without compromise to muscle mass and function

Mutations that reduce somatotropic signaling result in improved lifespan and health-span in model organisms and humans. However, whether reduced circulating insulin-like growth factor-I (IGF-I) level is detrimental to cognitive and muscle function in older adults remains understudied. A cross-sectio...

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Detalles Bibliográficos
Autores principales: Perice, Leland, Barzilai, Nir, Verghese, Joe, Weiss, Erica F., Holtzer, Roee, Cohen, Pinchas, Milman, Sofiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115897/
https://www.ncbi.nlm.nih.gov/pubmed/27744417
http://dx.doi.org/10.18632/aging.101063