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Lower circulating insulin-like growth factor-I is associated with better cognition in females with exceptional Longevity without compromise to muscle mass and function
Mutations that reduce somatotropic signaling result in improved lifespan and health-span in model organisms and humans. However, whether reduced circulating insulin-like growth factor-I (IGF-I) level is detrimental to cognitive and muscle function in older adults remains understudied. A cross-sectio...
Autores principales: | Perice, Leland, Barzilai, Nir, Verghese, Joe, Weiss, Erica F., Holtzer, Roee, Cohen, Pinchas, Milman, Sofiya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115897/ https://www.ncbi.nlm.nih.gov/pubmed/27744417 http://dx.doi.org/10.18632/aging.101063 |
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