Impaired autophagy activity is linked to elevated ER-stress and inflammation in aging adipose tissue

Adipose tissue dysfunction in aging is associated with inflammation, metabolic syndrome and other diseases. We propose that impaired protein homeostasis due to compromised lysosomal degradation (micro-autophagy) might promote aberrant ER stress response and inflammation in aging adipose tissue. Usin...

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Detalles Bibliográficos
Autores principales: Ghosh, Amiya Kumar, Mau, Theresa, O'Brien, Martin, Garg, Sanjay, Yung, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115904/
https://www.ncbi.nlm.nih.gov/pubmed/27777379
http://dx.doi.org/10.18632/aging.101083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115904/
https://www.ncbi.nlm.nih.gov/pubmed/27777379
http://dx.doi.org/10.18632/aging.101083

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