Efficacy of Ampicillin Against Methicillin-Resistant Staphylococcus aureus Restored Through Synergy with Branched Poly(ethylenimine)

Beta-lactam antibiotics kill Staphylococcus aureus bacteria by inhibiting the function of cell-wall penicillin binding proteins (PBPs) 1 and 3. However, β-lactams are ineffective against PBP2a, used by methicillin-resistant Staphylococcus aureus (MRSA) to perform essential cell wall crosslinking fun...

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Detalles Bibliográficos
Autores principales: Foxley, Melissa A., Friedline, Anthony W., Jensen, Jessica M., Nimmo, Susan L., Scull, Erin M., King, Jarrod R., Strange, Stoffel, Xiao, Min, Smith, Benjamin E., Thomas, Kieth J., Glatzhofer, Daniel T., Cichewicz, Robert H., Rice, Charles V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115998/
https://www.ncbi.nlm.nih.gov/pubmed/27189119
http://dx.doi.org/10.1038/ja.2016.44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115998/
https://www.ncbi.nlm.nih.gov/pubmed/27189119
http://dx.doi.org/10.1038/ja.2016.44

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