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SUMOylation and SENP3 regulate STAT3 activation in head and neck cancer

Hyperphosphorylation of signal transducer and activator of transcription 3 (STAT3) has been found in various types of human cancers, including head and neck cancer (HNC). Although smoking is critical in the development and progression of HNC, how tobacco components activate STAT3 is unclear. We demo...

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Detalles Bibliográficos
Autores principales: Zhou, Z, Wang, M, Li, J, Xiao, M, Chin, Y E, Cheng, J, Yeh, E T H, Yang, J, Yi, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116054/
https://www.ncbi.nlm.nih.gov/pubmed/27181202
http://dx.doi.org/10.1038/onc.2016.124